SPR for Aptamer-Based Molecular Interactions in Programmable Materials

photo of speaker Erin Gaddes

Erin Gaddes

PhD Candidate, Penn State University, Department of Bioengineering

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Surface plasmon resonance (SPR) is a sensitive, label-free technique that detects mass changes due to biomolecular interactions on a surface. This versatile method has been used to evaluate the specificity and binding kinetics of molecules, ranging from short oligonucleotides to whole cells. In this webinar, we will discuss the use of SPR to investigate interactions between aptamers and their targets, as well as the triggered formation of DNA polymers and polyvalent aptamers. In addition, the use of oligonucleotides for the release of protein drugs will be discussed.


NOTE: The video and audio in the first few minutes of the webinar are out of sync.