The best 2-channel SPR value you can buy
Choose the 2-channel surface plasmon resonance (SPR) system that lets you do more — and costs up to 30% less than the leading competitor. The Reichert2SPR System pushes the limits of detection and sensitivity, which is why it’s used by leading universities, academic facilities and biotech startups around the world for label-free biomolecular interaction analysis.
With Reichert, you get more, including:
- High-quality, publication-ready data
- The most sensitive, flexible and affordable 2-channel system available
- The best performance-to-cost ratio for individual labs
- A proven SPR leader since 1997
To see how Reichert can help advance your research and lead to new breakthroughs, contact us today to schedule a demo in your lab.Request a Demo
Lower Equipment Costs
Purchasing the Reichert2SPR System typically costs $25,000 less than the leading competitor.
Lower Operating Costs
Every SPR machine requires chips to couple proteins to. A typical lab can use 75–200 sensor chips each year, which is why you should always ask about the cost of chips when you’re considering an SPR system. At Reichert, our high-quality chips are often less than half the price of our competitors, so you can run more experiments without worrying about out-of-control costs.
No Costly Service Contract Required
Other SPR companies make you purchase a service contract, which can easily cost up to $150,000 over the course of five years. With the Reichert2SPR System, all of the typical parts that need maintenance are easy for you to access (and service) yourself. Of course, we do offer service contracts, if you would rather let us handle the regular maintenance.
Open System = High-Quality Data, More Flexibility
Interface With Other Modules For All-In-One Experimentation Options
Reichert’s open, component-based design lets you connect the Reichert2SPR System to other modules, and gain valuable new information in a single experiment.
Our specialized flow cells let you:
- Combine Reichert SPR with:
- Couple Reichert SPR with:
- Mass spectrometry
- Liquid chromatography
Automatic Or Semi-Automatic Systems That Work With User-Friendly Software
User-friendly Software Lets You Get Work Done Faster
Streamline your workflow with our powerful yet easy-to-use software. The simple drag-and-drop interface lets you quickly develop and execute experiments, including couple and capture experiments.
The Autolink software controls and analysis package features:
- 21 CFR part 11 controls
- Flexible, drag-and-drop experiment setup
- Streamlined data acquisition and analysis
- Flexible data analysis with multiple binding models
- Access controls to ensure data integrity
- Configurable authorization levels for creating and running experiments, options and data export
An SPR leader since 1997
Reichert is a name you can trust. We’ve been working with SPR technology since 1997, selling to some of the top names in academics and private industry. We’ve been in business for more than 140 years. And we’re backed by a billion-dollar company, AMETEK, Inc.
Personal Service And Attention, Whenever You Need It
At Reichert, we’re here for you — just as we have been for more than 20 years — with the expert service and support you expect from an industry leader.
- Product demo in your lab: We’ll bring a machine to your lab, set it up, and show you how to run your samples so you can see the results for yourself. Request a demonstration.
- In-person set-up and training: When you purchase a Reichert system, we’ll come to your lab to set everything up for you and help train your staff.
- Ongoing support and troubleshooting: If you ever have a question or problem, just give us a call or send an email. We’ll help you address any issues, at any time.
For Early-stage Life Sciences And Material Science Research
SPR is typically used in academic and industry settings to advance research in a range of areas, including:
- Antibody development
- Drug development and discovery
- Concentration analysis
- Gene regulation
- Pharmaceutical research
- Studying protein structure and function determination
- Systems biology
- Thermodynamics analysis (ΔH & ΔS)
Whether you’re studying Alzheimer’s disease, developing new vaccines or focused on other areas of protein research, SPR can help you quickly determine whether proteins interact, and which ones are worth studying more.
Determine The Binding Properties Of Biomolecular Interactions
SPR allows you to study a variety of interactions, including those involving:
- Nucleic acids
- Small molecules
With Reichert’s accessible tubing, you can also perform SPR on crude samples, including:
- Whole cells
Label-free Technique Saves You Time
With SPR, you work with native proteins, which means you don’t have to attach another molecule to one of your proteins. Instead, you’ll use our SPR device to immobilize one of your proteins on a small “chip,” and then flow your other protein or molecule over the chip to see the response and study the interaction.
SPR: More Data, Greater Accuracy Than Other Techniques
With SPR, you get a large volume of highly accurate information about protein interactions, including the strength of the interactions (affinities) and the binding kinetics — how fast the molecules are binding (associating) and dissociating. Other techniques don’t provide as much data and aren’t as accurate.
|Transducer Principle||Kretschmann prism, multiple angles from fixed light input
Measurement Channels – Two (either parallel or series fluid connection)
|Sample Loading||Autosampler or semi-automatic injector, standard HLPC tubing and connectors, external syringe pump|
|Sample Capacity||Any combination of up to 2 trays can be used. Choose: 12 (10 mL) or 48 (2 mL) vials; or 96-well (high or low) or 384-well plates|
|Sample Storage||4°C or ambient temperature|
|Flow Cell Volume (per channel) – 0.18 µL||Flow Cell Surface Area (per channel) – 4.5 mm² (reference value)|
|Aspect Ratio||> 25 (width/height)|
|Fluid Contact Materials||Teflon™, Acetal Copolymer, PEEK™, Kalrez™, ETFE (Tefzal™)|
|Sample Volume||20-4500 µL (depends on installed loop volume)|
|System Fluid Volume||28 µL (typically) (0.01" I.D. tubing) or 7.5 µL (0.005" I.D. tubing)|
|Temperature Range||10°C below ambient to 70°C|
|Refractive Index Resolution||< 10-7 RIU (< 0.1 µRIU)|
|Refractive Index Range||1.33 to 1.40 (@780nm)|
|Analyte Concentration Range||1 mM to 1 pM|
|Minimum Molecular Weight Detection||< 100 Daltons|
|Baseline Noise||0.1 µRIU peak-to-peak, 0.05 µRIU RMS, @ 25 mL/min|
|Baseline Drift||< 0.1 µRIU/min|
Typical Kinetic and Equilibrium Constant Ranges
|Association Rate Constant||103 to 107 M-1 s-1|
|Dissociation Rate Constant||10-1 to 10-5 s-1|
|Equilibrium Dissociation Constant||0.1 mM to 1 pM|
|Electrical||AC Power Supply, standard international voltage range w/universal adapter from 100 to 240 V; 50 to 60 Hz|
|Regulatory||Compliance with the applicable sections of the European EMC Directive and IEC safety requirements for laboratory electrical equipment for measurement and control|
|Product Safety||Compliance with IEC 61010-1 (Low Voltage Directive) under a Category classification EMC and Safety: CE mark certification (Class A, Type II)|
Compare the Reichert2SPR to Biacore's X100
The Reichert2SPR - Reichert’s SR7500DC system is the smart choice for scientists and lab managers. Reichert surface plasmon resonance instruments provide a highly sensitive and flexible platform to meet the demands of a variety of applications. In comparison with the Biacore X100, Reichert’s maintenance costs, autosampler capacity, and sensitivity make it the obvious choice.
|Number of Channels||2||2|
|Injection of Lysates, Cells, Particulates||✓Yes||No|
|Autosampler Capacity||✓Maximum 768 samples||15 samples|
|Baseline Drift||✓0.1 RU/min||< 0.3 RU/min|
|Baseline Noise||✓0.05 RU(RMS)||< 0.1 RU(RMS)|
|Sensor Chip Cost||✓$84 for dextran chip||$150 for dextran chip|
|Specialized Flow Cells||✓Electrochemistry, Photochemistry, Fluorescence, Mass Spectrometry||None|
|Sample Volume||✓20 – 4500 µL||20 – 30 µL (required)|
|Temperature Range||✓10°C below ambient to 70°C||4°C to 45°C (maximum 10°C below ambient)|
|Sample Compartment Temperature||✓4°C or Ambient||None|
|Flow Rate Range||✓0.1 – 3000 µL/min||1 – 100 µL/min|
|Minimum Molecular Weight Detection||✓< 100 Da||100 Da|
See for yourself how the Reichert4SPR System can help you make new discoveries. Contact us today, to set up a hands-on demonstration in your lab.