Sensor Chips
All of our chips are specifically chosen to provide optimum results when used with any Reichert SPR instrument (2-channel or 4-channel). Whether you are running a traditional biomolecular interaction analysis experiment or a more specialized assay, we have the slides you need.
- Affordable prices let you explore more interactions
- Protocols provided for each chip
- Academic discounts available when you place your order by phone (716-686-4522) or fax (716-686-4555)
- Custom coatings available (please contact us for details)
Which Chip Is Right For You?
Find your application to see which chips you need to run your experiments. If you have any questions, you can also contact us for technical expertise and advice.
Sensor Chip Buyer's Guide
Learn more about chips — and how to choose the right ones — with our Sensor Chip Buyer’s Guide.
Antibodies: Low-Capacity
- Surface: bare gold
- Study surface formation and adsorption in real-time
- Add your own surface coatings
- Can also be used for SPR Electrochemistry experiments
- Surface: Planar PEG with 10% COOH
- Minimizes non-specific binding, and provides a functional attachment site for immobilizing/capturing a molecule of interest
- Use for large/medium sized molecules along with viruses and cells
- Surface: NeutrAvidin
- Minimal biotinylation of the ligand and subsequent capture results in a more oriented arrangement of ligand molecules on the surface
- Use for capture of biotinylated molecules such as proteins, peptides, and nucleic acids
- Surface: Protein A
- Optimal binding occurs at pH 8.2, although binding is also effective at neutral or physiological conditions (pH 7.0 to 7.6)
- Use for capturing Fc region from IgG of several species including human and rabbit
- Low capacity chip used for interactions between large molecules
- Surface: Streptavidin
- Minimal biotinylation of the ligand and subsequent capture results in a more oriented arrangement of ligand molecules on the surface
- Use for capture of biotinylated molecules such as proteins, peptides, and nucleic acids
- Surface: Streptavidin
- Minimal biotinylation of the ligand and subsequent capture results in an oriented arrangement of ligand molecules on the surface
- Use for high affinity capture of biotinylated molecules such as proteins, peptides, and nucleic acids
Antibodies: High-Capacity
- Surface: bare gold
- Study surface formation and adsorption in real-time
- Add your own surface coatings
- Can also be used for SPR Electrochemistry experiments
- Surface: Carboxymethyl Dextran Hydrogel
- A stable surface resistant to non-specific binding
- Use for large/medium sized molecules and their interactions with low molecular weight molecules
- Surface: Protein A
- Optimal binding occurs at pH 8.2, although binding is also effective at neutral or physiological conditions (pH 7.0 to 7.6)
- Use for capturing Fc region from IgG of several species including human and rabbit
- High capacity chip used for interactions between small molecules and peptides with large molecules or interactions between large molecules.
- Surface: Polycarboxylate Hydrogel
- Provides another choice for high capacity coupling when studying protein-small molecule interactions or when dextran is not ideal
- Must purchase a 0.3mm flow cell
- Use for large/medium sized molecules and low molecular weight molecules
- Surface: Streptavidin
- Minimal biotinylation of the ligand and subsequent capture results in an oriented arrangement of ligand molecules on the surface
- Use for high affinity capture of biotinylated molecules such as proteins, peptides, and nucleic acids
- Surface: Nickel Nitrilotriacetic Acid
- High capacity capture works well even for protein-small molecule interactions
- Must purchase a 0.3 mm flow cell
- Use for capture of Poly His-tagged Molecules
- Results in an oriented capture
- Chip can be reused as long as capture is reversible
Carbohydrates
- Surface: bare gold
- Study surface formation and adsorption in real-time
- Add your own surface coatings
- Can also be used for SPR Electrochemistry experiments
- Surface: Planar PEG with 10% COOH
- Minimizes non-specific binding, and provides a functional attachment site for immobilizing/capturing a molecule of interest
- Use for large/medium sized molecules along with viruses and cells
- Surface: Carboxymethyl Dextran Hydrogel
- A stable surface resistant to non-specific binding
- Use for large/medium sized molecules and their interactions with low molecular weight molecules
- Surface: Polycarboxylate Hydrogel
- Provides another choice for high capacity coupling when studying protein-small molecule interactions or when dextran is not ideal
- Must purchase a 0.3mm flow cell
- Use for large/medium sized molecules and low molecular weight molecules
Lipids
A hydrophobic chip works best for capturing lipids. These chips are usually simple to regenerate using 20mM CHAPS.
- Surface: bare gold
- Study surface formation and adsorption in real-time
- Add your own surface coatings
- Can also be used for SPR Electrochemistry experiments
- Surface: Planar Hydrophobic
- Employs a long chain alkanethiol self-assembled monolayter (SAM) on the surface
- Use to study lipid binding
Proteins
Generally, planar chips can be used when studying protein-protein interactions. Dextran or other hydrogels can also be used.
Using Tags?
Choose Streptavidin or NeutrAvidin chips for targets with a biotin tag, and Ni-NTA for chips for targets with a His-tag.
Proteins: Low-Capacity
- Surface: bare gold
- Study surface formation and adsorption in real-time
- Add your own surface coatings
- Can also be used for SPR Electrochemistry experiments
- Surface: Planar PEG with 10% COOH
- Minimizes non-specific binding, and provides a functional attachment site for immobilizing/capturing a molecule of interest
- Use for large/medium sized molecules along with viruses and cells
- Surface: Nickel NTA
- Captured molecule is oriented on the surface via its histidine tag
- Use to capture histidine-tagged molecules such as recombinant proteins
- Surface: NeutrAvidin
- Minimal biotinylation of the ligand and subsequent capture results in a more oriented arrangement of ligand molecules on the surface
- Use for capture of biotinylated molecules such as proteins, peptides, and nucleic acids
- Surface: Streptavidin
- Minimal biotinylation of the ligand and subsequent capture results in a more oriented arrangement of ligand molecules on the surface
- Use for capture of biotinylated molecules such as proteins, peptides, and nucleic acids
Proteins: High-Capacity
- Surface: bare gold
- Study surface formation and adsorption in real-time
- Add your own surface coatings
- Can also be used for SPR Electrochemistry experiments
- Surface: Carboxymethyl Dextran Hydrogel
- A stable surface resistant to non-specific binding
- Use for large/medium sized molecules and their interactions with low molecular weight molecules
- Surface: Polycarboxylate Hydrogel
- Provides another choice for high capacity coupling when studying protein-small molecule interactions or when dextran is not ideal
- Must purchase a 0.3mm flow cell
- Use for large/medium sized molecules and low molecular weight molecules
- Surface: Streptavidin
- Minimal biotinylation of the ligand and subsequent capture results in an oriented arrangement of ligand molecules on the surface
- Use for high affinity capture of biotinylated molecules such as proteins, peptides, and nucleic acids
- Surface: Nickel Nitrilotriacetic Acid
- High capacity capture works well even for protein-small molecule interactions
- Must purchase a 0.3 mm flow cell
- Use for capture of Poly His-tagged Molecules
- Results in an oriented capture
- Chip can be reused as long as capture is reversible
Nucleic Acids
- Surface: bare gold
- Study surface formation and adsorption in real-time
- Add your own surface coatings
- Can also be used for SPR Electrochemistry experiments
- Surface: Planar PEG with 10% COOH
- Minimizes non-specific binding, and provides a functional attachment site for immobilizing/capturing a molecule of interest
- Use for large/medium sized molecules along with viruses and cells
- Surface: NeutrAvidin
- Minimal biotinylation of the ligand and subsequent capture results in a more oriented arrangement of ligand molecules on the surface
- Use for capture of biotinylated molecules such as proteins, peptides, and nucleic acids
- Surface: Polycarboxylate Hydrogel
- Provides another choice for high capacity coupling when studying protein-small molecule interactions or when dextran is not ideal
- Must purchase a 0.3mm flow cell
- Use for large/medium sized molecules and low molecular weight molecules
- Surface: Streptavidin
- Minimal biotinylation of the ligand and subsequent capture results in a more oriented arrangement of ligand molecules on the surface
- Use for capture of biotinylated molecules such as proteins, peptides, and nucleic acids
- Surface: Streptavidin
- Minimal biotinylation of the ligand and subsequent capture results in an oriented arrangement of ligand molecules on the surface
- Use for high affinity capture of biotinylated molecules such as proteins, peptides, and nucleic acids
Small Molecules
- Surface: bare gold
- Study surface formation and adsorption in real-time
- Add your own surface coatings
- Can also be used for SPR Electrochemistry experiments
- Surface: Carboxymethyl Dextran Hydrogel
- A stable surface resistant to non-specific binding
- Use for large/medium sized molecules and their interactions with low molecular weight molecules
- Surface: Polycarboxylate Hydrogel
- Provides another choice for high capacity coupling when studying protein-small molecule interactions or when dextran is not ideal
- Must purchase a 0.3mm flow cell
- Use for large/medium sized molecules and low molecular weight molecules
- Surface: Streptavidin
- Minimal biotinylation of the ligand and subsequent capture results in an oriented arrangement of ligand molecules on the surface
- Use for high affinity capture of biotinylated molecules such as proteins, peptides, and nucleic acids
- Surface: Nickel Nitrilotriacetic Acid
- High capacity capture works well even for protein-small molecule interactions
- Must purchase a 0.3 mm flow cell
- Use for capture of Poly His-tagged Molecules
- Results in an oriented capture
- Chip can be reused as long as capture is reversible