Small Molecules
Sensor Chips
Plain Gold Surface
Sensor Chip
- Surface: bare gold
- Study surface formation and adsorption in real-time
- Add your own surface coatings
- Can also be used for SPR Electrochemistry experiments
Carboxymethyl Dextran Hydrogel Surface
Sensor Chip
- Surface: Carboxymethyl Dextran Hydrogel
- A stable surface resistant to non-specific binding
- Use for large/medium sized molecules and their interactions with low molecular weight molecules
Polycarboxylate Hydrogel
Sensor Chip
- Surface: Polycarboxylate Hydrogel
- Provides another choice for high capacity coupling when studying protein-small molecule interactions or when dextran is not ideal
- Must purchase a 0.3mm flow cell
- Use for large/medium sized molecules and low molecular weight molecules
Streptavidin Covalently Immobilized on a Carboxymethyl Dextran Surface
Sensor Chip
- Surface: Streptavidin
- Minimal biotinylation of the ligand and subsequent capture results in an oriented arrangement of ligand molecules on the surface
- Use for high affinity capture of biotinylated molecules such as proteins, peptides, and nucleic acids
High Capacity Nickel Nitrilotriacetic Acid Surface 200M
Sensor Chip
- Surface: Nickel Nitrilotriacetic Acid
- High capacity capture works well even for protein-small molecule interactions
- Must purchase a 0.3 mm flow cell
- Use for capture of Poly His-tagged Molecules
- Results in an oriented capture
- Chip can be reused as long as capture is reversible