Features:
- Quality Kinetic and Thermodynamic Data at an Affordable Price
- Monitors Surface Plasmon Resonance and Critical Angle Responses
- Response vs. Time and Reflectivity Data
- System is HPLC fluidics based
a) User serviceable
b) Nano to micro to macro applications
c) 0.0025" to 0.04" I.D. Tubing
d) Allows flow of cell lysates
- Sapphire Prism
a) Virtually indestructible
b) High thermal conductivity contributes to exceptional thermal stability
- 10 Deg. C. to 90 Deg. C. Temperature Range
a) Temperature changes programmable in user defined steps and intervals
b) Change temperature in minutes not hours
c) Kinetic capability over a broad temperature range
- Macromolecular to Small Molecule Binding
- Broad Refractive Index Range
- Sensitivity: 0.75 µ Refractive Index Units rms.
- Easily Automated with Addition of an Autosampler
- Available Large Surface Area Flow Cell
- Available Cuvette Sample Option
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Applications:
- Widely used for but not limited to determining Protein/Protein, Protein/Peptide, DNA/Protein, and Drug/Protein interactions
- Relative Binding Affinities
- Kinetic rate constants (on-forward-association, off-reverse-dissociation)
- Thermodynamics (Association and Dissociation Equilibrium Constants)
- Concentration monitoring
- Sequence recognition, Epitope screening and mapping
- Ligand fishing
- Method development – before running more expensive tests
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